Gene Editing in Clinical Practice
نویسندگان
چکیده
منابع مشابه
Frequency of Errors in Clinical Laboratory Practice
Background and Objective: Laboratory errors are one of the major factors that affect the diagnosis, prognosis, treatment and monitoring in patients.The objective of study is to evaluate the frequency and type of errors in different phases of testing at the Pathology Department of the Shalamar Hospital, Lahore and to evaluate the causes of errors. Methods: This observational study was carrie...
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Kok et al. conclude that results with Morpholino oligos, which are not recapitulated by natural mutations or gene editing mutations, must be due to off-target effects and, when morphants and mutants differ, they contend that antisense oligo studies should be disregarded. Morpholinos and gene editing mutagenesis are very different technologies and, even if both work perfectly, may yield differen...
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OBJECTIVES/HYPOTHESIS Gene expression classifiers can safely reduce diagnostic thyroid surgery for fine-needle aspiration cytology (FNAC) indeterminate thyroid nodules. STUDY DESIGN Retrospective review, single-institution, single-practice surgeon. METHODS Three-year retrospective review of indeterminate FNAC that went on to gene expression classifier testing. RESULTS A total of 520 patie...
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T he current kerfuffle around the use of CRISPR/Cas9 and other gene editing technologies in human germline research is the latest in a series of related controversies at the intersection of science, medicine, and ethics [1]. Soon after a prominent ad hoc group of scientists called for a moratorium on clinical applications of germline gene editing [2], a research group from China published an ar...
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Targeted gene editing could offer tremendous advantages over traditional plant breeding to create new cultivars with advantageous combinations of alleles, especially when stacking of important traits is needed for crop improvement. Traditional methods of combining desirable alleles of different genes involve time-consuming crosses and selections, and in some cases such as combining closely link...
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ژورنال
عنوان ژورنال: Indian Journal of Clinical Biochemistry
سال: 2017
ISSN: 0970-1915,0974-0422
DOI: 10.1007/s12291-017-0720-z